GL-3446
Compound name(s): α2,3-sialyllactose, 3’sialyllactose, or 3’SL bearing an aminopentanol anomeric linker.
Anomeric linker: 5-amino-1-pentanol
Chemical formula: C28H49N2O19Na
Physical state of bulk product: White, fluffy solid
Molar mass: 740.68
Compound information: As one of the most abundant sialylated human milk oligosaccharides, it serves as a reference structure in studies of infant gut microbiota modulation and pathogen decoy activity. Additionally, 3’sialyllactose is also the carbohydrate portion of the GM3 ganglioside. With the aminopentanol linker, this compound can be immobilized on glycan microarrays to profile the α2,3/α2,6 selectivity of viral adhesions, carbohydrate-recognizing proteins, and other sialic-acid-binding lectins, or used to generate neoglycoconjugates for receptor-specificity ELISAs.
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QC report for GL-3446
References (links open in a new tab):
1. Yang, M., Jiang, Z., Zhou, L., Chen, N., He, H., Li, W., … Lu, Z. 3’-Sialyllactose and B. infantis synergistically alleviate gut inflammation and barrier dysfunction by enriching cross-feeding bacteria for short-chain fatty acid biosynthesis. Gut Microbes 2025, 17(1).
2. Lars Bode, Human milk oligosaccharides: Every baby needs a sugar mama, Glycobiology 2012, 22 (9), 1147–1162.